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Accutane (manufactured by the pharmaceutical company Roche) is a treatment that could be called “a shock” in the form of tablets to cure moderate to very severe acne, made of isotretinoin (vitamin A derivative), prescribed by the doctor. Unlike many topical or internal treatment with antibiotics that should be repeated after some time or frequently, it often seems more effective in the long term.
The patients who take Accutane must generally respect the treatment for a minimum of 3 to 4 months. Subsequently, the doctor will assess the results and may or may not prescribe a second treatment of similar length. It is less common for a patient to use a third treatment.
Because of its teratogenicity (prohibition of getting pregnant given the high risk of fetal deformities), patients are required to take the contraceptive pill. This will frequently be continued for 12 months after the completion of the treatment to avoid the risk of deformities that persists during this period.
Accutane affects everyone in a different way and has several possible side effects:
- Cardiovascular problem;
- Digestive problem;
- Liver disorder;
- Risk of depression;
- Nosebleed;
- Dry skin and eyes;
- Bone and muscle problems
The following blood tests are usually required before and during the treatment
- Determination of serum lipids (cholesterol, triglycerides);
- Complete blood count (platelets, red blood cells and white blood cells);
- Liver function tests (liver enzymes);
- Blood glucose (sugar) especially in known or suspected diabetes cases.